Determination of the Activity of Diclazuril against Sarcocystis neurona and Sarcocystis falcatula in Cell Cultures
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چکیده
منابع مشابه
Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures.
Diclazuril is a benzeneacetonitril anticoccidial that has excellent activity against the extraintestinal stages of Toxoplasma gondii and Neospora caninum. It also is highly active against intestinal coccidia of poultry. The present study examined the efficacy of diclazuril in inhibiting merozoite production of Sarcocystis neurona and Sarcocystis falcatula in bovine turbinate cell cultures. Dicl...
متن کاملDevelopment of Sarcocystis falcatula in cell cultures demonstrates that it is different from Sarcocystis neurona.
The development of Sarcocystis falcatula merozoites in bovine turbinate (BT) cell cultures is described and compared with development of Sarcocystis neurona merozoites. Merozoites of S. falcatula entered BT cell cultures and increased in size until 3 days post-inoculation when the nucleus of some merozoites developed lobes. Developing schizonts present at 4 days contained a lobed nucleus or app...
متن کاملDetermination of the activity of ponazuril against Sarcocystis neurona in cell cultures.
The present study examined the efficacy of ponazuril in inhibiting merozoite production of Sarcocystis neurona in cell cultures. Ponazuril inhibited merozoite production by more that 90% in cultures of S. neurona treated with 1.0 microg/ml ponazuril and greater than 95% inhibition of merozoite production was observed when infected cultures were treated with 5.0 microg/ml ponazuril. Ponazuril ma...
متن کاملComparative development and merozoite production of two isolates of Sarcocystis neurona and Sarcocystis falcatula in cultured cells.
The development and merozoite production of Sarcocystis falcatula and 2 isolates (SN6 and SN2) of Sarcocystis neurona were studied in various cultured cell lines inoculated with culture-derived merozoites. All 3 parasites underwent multiple cycles of schizogony in VERO cells, bovine monocytes (M617 cells), and bovine pulmonary artery endothelial cells (CPA). Sarcocystis neurona strains SN6 and ...
متن کاملSerologic responses of cats against experimental Sarcocystis neurona infections.
Sarcocystis neurona is the most important cause of a neurologic disease of horses, equine protozoal myeloencephalitis (EPM). Cats and other carnivores can act as its intermediate hosts and horses are aberrant hosts. Little is known of the sero-epidemiology of S. neurona infections in cats. In the present study, antibodies to S. neurona were evaluated by the S. neurona agglutination test (SAT). ...
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ژورنال
عنوان ژورنال: The Journal of Parasitology
سال: 2000
ISSN: 0022-3395
DOI: 10.2307/3284931